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Chinese Journal of Integrative Nursing ›› 2021, Vol. 7 ›› Issue (10): 88-92.DOI: 10.12209/j.issn2709-1961.202108039

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Effect of Shubishu biocolloids combined with compound Huangbai Solution lotion in the treatment of diabetic foot ulcer

GAN Lu1, XIE Wei2, JIANG Yonghong1, ZHANG Youqiong1, YUAN Dan1, CHEN Yuanyuan1, MO Mei1, GONG Xuelei1   

  1. 1. Department of Endocrinology, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, 550001; 2. Department of Nursing, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, 550001
  • Online:2021-10-31 Published:2021-11-11

Abstract: Objective  To observer the effect of Shubishu biocolloids combined with compound Huangbai Solution lotion in the treatment of diabetic foot ulcer, and evaluate its  efficacy and safety. Methods  A Total of 24 patients with refractory diabetic foot ulcer were divided into the observation group and control group, with 12 cases in each group. All patients received routine treatment, and those in the observation group were given external application of Shubishu biocolloids combined with compound Huangbai Solution lotion. The wound healing condition, degree of pruritus, pain, granulation tissue at wound surface area and wound infection condition were assessed at 8 weeks after intervention. Results  The overall response rate was 91.67%(11/12)in the observation group, which was higher than 58.33%(7/12)in the control group(P<0.05). The scores of assessment on pruritus, pain, granulation tissue decreased in both two group at 8 weeks after intervention(P<0.05), and scores of pruritus, pain, granulation tissue assessment in the observation group were lower than those in the control group (P<0.05). There were 2 cases of wound infection reported in the control group. Conclusion  The Shubishu biocolloids combined with compound Huangbai Solution lotion is effective and safe to improve the efficacy of treatment for diabetic foot ulcer, relieve general symptoms, reduce ulcer area.

Key words: diabetic foot ulcer, biocolloids, compound Huangbai Solution, diabetes mellitus, infection 

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